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Mouse T1/ST2 Monoclonal Antibody
rat anti-mouse T1/ST2 mAb-FITC Conjugated
Mouse T1/ST2 Monoclonal Antibody
rat anti-mouse T1/ST2 mAb-FITC Conjugated
- 中文名称：
- Mouse T1/ST2 Monoclonal Antibody
rat anti-mouse T1/ST2 mAb-FITC Conjugated
- 英文名称：
- Mouse T1/ST2 Monoclonal Antibody
rat anti-mouse T1/ST2 mAb-FITC Conjugated
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA63026
- 规格：
- 0.5 mL|2x0.5 mL|3x0.5 mL|4x0.5 mL|5x0.5 mL
- 保存建议：
- Store 2-8 degree C. Protect from the light
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- N/A
- 应用：
- IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1 (light chain not isotyped)
克隆号:[DJ8]
特异性:This clone recognizes the membrane anchored murine T1M protein on the surface of T helper 2 cells and mast cells. T1M appears on fetal blood derived mast cell progenitors before they express the Fce RI, on IL-3-dependent bone marrow derived mast cells and on mature peritoneal mast cells. The antibody detects T1S protein consisting only of the extracellular portion of the protein, which is secreted from growth factor and proinflammatory cytokine-stimulated murine fibroblasts.
纯度:N/A
形式：The antibody is supplied in PBS, with 0.1% sodium azide as preservative and purified over protein G-sepharose. The characteristics of each lot are tested by FACS analysis with bone marrow derived mast cells.
浓度：1mg/ml
- 说明书：
Mouse T1/ST2 (IL-33 R) FITC conjugated monoclonal antibody (clone DJ8) for the identification and purification of murine T helper 2 (Th2) cells and all forms of murine mast cells.
Overview: T1/ST2 (also known as IL-1 R4 or IL-33Ra) is a transmembrane glycoprotein expressed on mast cells and Th2 cells. It is a selective marker for both murine and human Th2 lymphocytes and plays a role in regulating inflammatory responses. IL-33 is a recently identified member of the IL-1 family of cytokines and is involved in Th2 mediated immune responses. IL-33 mediates its biological effects via T1/ST2 binding. The roles of IL-33 and T1/ST2 (IL-33Ra) have been investigated in many immune responses such as allergy, asthma, rheumatoid arthritis and osteoarthritis.
