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Mouse Anti Keratin 8 (pS431) Monoclonal Antibody
Mouse Anti Keratin 8 (pS431) Monoclonal Antibody
- 中文名称：
- Mouse Anti Keratin 8 (pS431) Monoclonal Antibody
- 英文名称：
- Mouse Anti Keratin 8 (pS431) Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71350
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The antibodies are stable for up to 12 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2 to 8°C for up to three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Mouse, Rat
- 应用：
- ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:N/A
特异性:N/A
纯度:Protein A Chromatography
形式：This affinity purified antibody is supplied in Sterile Phosphate Buffered saline (pH7.2) containing antibody stabilizer.
浓度：N/A
- 说明书：
Keratins are cytoplasmic intermediate filament proteins preferentially expressed by epithelial tissues in a site-specific and differentiation-dependent manner. The complex network of keratin filaments in stratified epithelia is tightly regulated during squamous cell differentiation. Keratin 8 and 18 (K8/18) phosphorylation, such as K8 (S23, S73, S431) and K18 (S33, S52), plays a significant and site-specific role in regulating keratin filament organization, association with binding proteins, and modulation of cell cycle progression. Keratin hyperphosphorylation correlates with exposure to a variety of stresses in cultured cells and in mouse models of liver, pancreatic, and gallbladder injury, and it is found in assocation with mouse and human Mallory bodies. The increase of site-specific keratin phosphorylation in liver disease might be a progression marker.
