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alpha Synuclein
alpha Synuclein
- 中文名称：
- alpha Synuclein
- 英文名称：
- alpha Synuclein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA76715
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Chicken
- 反应种属：
- Human, Mouse, Rat, Bovine, Porcine, Equine
- 应用：
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Chicken IgY
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Liquid. Affinity purified antibody at 1mg/mL in 50% PBS, 50%glycerol plus 5mM NaN3
浓度：N/A
- 说明书：
alpha-synuclein is a member of the synuclein protein family, the other two members being beta and gamma synuclein, each protein being coded for by a distinct but related gene. alpha-synuclein was originally isolated as a major synaptic vesicle associated protein from the electric organ of the fish Torpedo, and direct homologues of alpha-synuclein are found in all vertebrates. Later work connected alpha-synuclein expression with several human brain pathologies, so that it is a major component of the Lewy bodies of Parkinson's disease. Point mutations of alpha-synuclein proved to be causative of some forms of familial Parkinson's disease. alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy and amyotrophic lateral sclerosis. alpha-synuclein is normally heavily expressed in brain and appears to be localized primarily to presynaptic regions, though not with a typical synaptic vesicle distribution pattern.
This antibody recognizes full length human and rodent alpha-synuclein specifically both in western blots and in immunocytochemical experiments and is a good marker of synapses on transgenic mice.
