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FOX3/NeuN
FOX3/NeuN
- 中文名称：
- FOX3/NeuN
- 英文名称：
- FOX3/NeuN
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA76718
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Goat
- 反应种属：
- Human, Mouse, Rat
- 应用：
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Goat IgG
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Liquid. Affinity purified antibody at 1mg/mL in 50% PBS, 50%glycerol plus 5mM NaN3
浓度：N/A
- 说明书：
NeuN has become very widely used as a reliable neuronal marker, apparently binding to neurons in all vertebrates tested. The vast majority of neurons are strongly NeuN positive, and NeuN immunoreactivity has therefore been widely used to identify neurons. The differing protein isoforms of FOX3 result from alternate splicing of two exons which code for an insert close to the C-terminus and a short C-terminal extension. The extension includes a C-terminal proline-tyrosine sequence preceded by hydrophobic amino acids (phi-PY) which is known to target proteins to the nucleus, apparently accounting for FOX3 being present in both nuclei and cytoplasm in certain neurons.
This antibody was raised against a recombinant human FOX3 construct based only on the N-terminal sequence, not including the RRM domain and C-terminal regions. The N-terminal regions of FOX1, FOX2 and FOX3 are relatively poorly conserved so we were able to obtain antibodies which recognized FOX3 but not FOX2 or FOX1.
