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GFAP
GFAP
- 中文名称:
- GFAP
- 英文名称:
- GFAP
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA76727
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human, Mouse, Rat, Bovine, Porcine
- 应用:
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:Mouse IgG1
克隆号:N/A
特异性:N/A
纯度:N/A
形式:Liquid. Purified at 1mg/mL in PBS, 50% glycerol, 5mM NaN3
浓度:N/A
- 说明书:
Glial fibrillary acidic protein (GFAP) is strongly and specifically expressed in astrocytes, Bergmann glia, certain other glia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. GFAP expression is also seen in developing neural stem cells and GFAP levels may greatly increase in regions of CNS injury or disease. The formation of a GFAP rich "glial scar" following CNS injury may be one reason why reconnection of severed processes is relatively inefficient in adults.
This antibody was made against a recombinant construct containing amino acids 71-217 of the human isotype 1 sequence in NP_002046.1. This region is somewhat variable between species so antibodies to this human construct may be superior on human cells, tissues and for biomarker assays of human proteins. It has a KD of 6.157 X 10-10M. High quality antibodies to GFAP, like MO22205, are useful for visualizing glia and monitoring developmental, disease and damage related CNS alterations and for ELISA and bead based type assays.