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STAM Mouse Monoclonal Antibody (G1G5)
STAM Mouse Monoclonal Antibody (G1G5)
- 中文名称：
- STAM Mouse Monoclonal Antibody (G1G5)
- 英文名称：
- STAM Mouse Monoclonal Antibody (G1G5)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77826
- 规格：
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议：
- Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Mouse, Rat, Human
- 应用：
- WB (Western Blot), IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:N/A
克隆号:[G1G5]
特异性:The antibody recognizes the STAM1 and STAM2.
纯度:N/A
形式：Lyophilized protein G purified in PBS pH7.4
浓度：N/A
- 说明书：
The signal transducing adapter molecule 1 (STAM1) and signal transducing adapter molecule 2 (STAM2) are regulators of receptor signalling and trafficking. STAM interacts with the hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) to form a heterodimeric complex which mediates the endocytic sorting of ubiquitinated membrane proteins. Studies have demonstrated that the complex STAM/Hrs is tyrosine-phosphorylated in response to a variety of growth factors including EGF, HGF and PDGF. STAM1 and STAM2 phosphorylation occurs on tyrosines upon stimulation with cytokines through the Jak3 signaling pathway, which is essential for T-cell development. STAM has an important role in T-cell development and survival in the thymus through the prevention of apoptosis but is not necessary for the proximal signaling of TCR and cytokine receptors.
