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Phospho-AKT1(S129) Antibody Blocking peptide
Phospho-AKT1(S129) Antibody Blocking peptide
- 中文名称：
- Phospho-AKT1(S129) Antibody Blocking peptide
- 英文名称：
- Phospho-AKT1(S129) Antibody Blocking peptide
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA290792
- 规格：
- 0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg|5x0.5 mg
- 保存建议：
- Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery.
