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Recombinant mouse IL-17A protein
Recombinant mouse IL-17A protein
- 中文名称：
- Recombinant mouse IL-17A protein
- 英文名称：
- Recombinant mouse IL-17A protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48986
- 规格：
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE
- 产品形式：
- Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
IL-17A, also known as CTLA?8, is a cytokine that belongs to the Interleukin?17 family. It produced by activated T cells and plays an important role in anti?microbial and chronic inflammation. Mouse IL?17A shares 61% amino acid sequence identity with human IL?17A. It promotes protective mucosal and epidermal inflammation in response to microbial infection and induces chemokine production, neutrophil influx, and the production of antibacterial peptides. It can stimulate the expression of IL-6 and PTGS2/COX-2, as well as enhance the production of nitric oxide(NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis. Also, IL?17A has been shown to exert either tumorigenic or anti?tumor effects. Recombinant mouse IL-17A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
