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Recombinant Human Fc epsilon RI alpha protein
Recombinant Human Fc epsilon RI alpha protein
- 中文名称：
- Recombinant Human Fc epsilon RI alpha protein
- 英文名称：
- Recombinant Human Fc epsilon RI alpha protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48987
- 规格：
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|5x0.01 mg
- 保存建议：
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Fc epsilon RI alpha, also known as FCER1A, is an IgE?binding protein of the multichain immune recognition family. Fc epsilon receptor is a tetrameric complex of one alpha, one beta and two gamma subunits on mast cells and basophils. This protein represents the alpha subunit, only the alpha subunit is glycosylated. The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes—potent effectors of the hypersensitivity response. Recombinant human Fc epsilon RI alpha/FCER1A, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
