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Recombinant MRCKb/CDC42BPB (1-473) protein
Recombinant MRCKb/CDC42BPB (1-473) protein
- 中文名称：
- Recombinant MRCKb/CDC42BPB (1-473) protein
- 英文名称：
- Recombinant MRCKb/CDC42BPB (1-473) protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA60315
- 规格：
- 0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg|5x0.02 mg
- 保存建议：
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 货期：
- 6-8周
- 纯度：
- >95%
- 产品形式：
- Recombinant MRCKb/CDC42BPB(1-473) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
CDC42BPB (CDC42 Binding Protein Kinase Beta) is a serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. This protein regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1 CDC42BPB is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. In concert with FAM89B/LRAP25 CDC42BPB mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.
