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Recombinant RPS6KA1/RSK1 protein
Recombinant RPS6KA1/RSK1 protein
- 中文名称:
- Recombinant RPS6KA1/RSK1 protein
- 英文名称:
- Recombinant RPS6KA1/RSK1 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA60316
- 规格:
- 0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg|5x0.02 mg
- 保存建议:
- Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 货期:
- 6-8周
- 纯度:
- >=90%
- 产品形式:
- Recombinant RPS6KA1/RSK1 protein is supplied in 25 mM HEPES NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
RPS6KA1-(Ribosomal Protein S6 Kinase A1) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77. This protein regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. Diseases associated with RPS6KA1 include Coffin-Lowry Syndrome and Tuberous Sclerosis.