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Human Galectin-3
Human Galectin-3
- 中文名称：
- Human Galectin-3
- 英文名称：
- Human Galectin-3
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79140
- 规格：
- 0.01 mg|0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg
- 保存建议：
- The lyophilized protein is stable for a 1 month at room temperature or 6 months at 4 degree C. The reconstituted protein is stable for 1 week at 2 degree C to 8 degree C and 3 months at -20 degreeC to 8 degree c and 3 months at -20 degree C to -80 degree C. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (e.g. 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- > 98% by SDS-PAGE and HPLC analysis
- 产品形式：
- Lyophilized from 0.5x PBS, pH 7.2
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine. Recombinant human Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues, but no disulfide bonds.
