-
Human CYR61
Human CYR61
- 中文名称：
- Human CYR61
- 英文名称：
- Human CYR61
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79141
- 规格：
- 0.005 mg|0.02 mg|2x0.02 mg|3x0.02 mg|4x0.02 mg
- 保存建议：
- The lyophilized protein is stable at room temperature for up to 1 month. Working aliquots stored with a carrier protein are stable for at least 5 months at -20 degree C to -80 degree C. Avoid repeated freeze thaw cycles.
- 货期：
- 6-8周
- 纯度：
- > 95% by SDS-PAGE and HPLC analysis
- 产品形式：
- Lyophilized from 10 mM Sodium Citrate, pH 3.0 + 50mM NaCl
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
CYR61 is a member of the CCN family of secreted cysteine rich regulatory proteins. CYR61 induces angiogenesis by stimulating the proliferation, migration, and adhesion of endothelial cells. Cell migration and adhesion are mediated through binding to specific cell surface integrins and to heparin sulfate proteoglycans. Increased expression of CYR61 is associated with several types of cancer, and correlates with the progression and estrogen independence of human breast cancers. Recombinant human CYR61 is a 39.5 kDa protein containing 357 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the Thrombospondin type-I (TSP type-1) domain, and a C-terminal cysteine knot-like domain (CTCK).
