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Anti-Peripherin Antibody
Anti-Peripherin Antibody
- 中文名称：
- Anti-Peripherin Antibody
- 英文名称：
- Anti-Peripherin Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- 1631-PERt
- 规格：
- 25 µL
- 保存建议：
- Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
- 背景资料：
- Peripherin is a ~57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury (1). Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors (2). Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes (3). Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration.
- 货期：
- 3-4周
- 来源宿主：
- Chicken
- 反应种属：
- Bovine, Human, Mouse, and Rat
- 应用：
- ELISA, WB, IHC, ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:21.5 mg/ml
推荐稀释比（WB）:1:1000
推荐稀释比（WB Brain）:1:1000
推荐稀释比（IHC）:1:500-1:2000
推荐稀释比（ICC）:1:500-1:5000
- 说明书：
Our Anti-Peripherin primary antibody from PhosphoSolutions is chicken polyclonal. It detects bovine, human, mouse, and rat Peripherin and is total IgY fraction. It is great for use in WB, IHC, ICC.
