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Anti-Potassium Chloride Cotransporter (KCC2) (Ser940) Antibody
Anti-Potassium Chloride Cotransporter (KCC2) (Ser940) Antibody
- 中文名称：
- Anti-Potassium Chloride Cotransporter (KCC2) (Ser940) Antibody
- 英文名称：
- Anti-Potassium Chloride Cotransporter (KCC2) (Ser940) Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- p1551-940t
- 规格：
- 25 µL
- 保存建议：
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- 背景资料：
- KCC2 is widely thought to be expressed exclusively in neurons where it is responsible for maintaining low intracellular chloride concentration to drive hyperpolarizing post-synaptic responses to the inhibitory neurotransmitters GABA and glycine. Serine 940 on KCC2 has been shown to be phosphorylated by PKC and has further been demonstrated to be the major site for PKC-dependent phosphorylation for full length KCC2 molecules when expressed in HEK-293 cells as phosphorylation of Ser-940 increased the cell surface stability of KCC2 in this system by decreasing it’s rate of internalization from the plasma membrane (Lee et al., 2007).
- 货期：
- 3-4周
- 来源宿主：
- Rabbit
- 反应种属：
- Mouse and Rat
- 应用：
- ELISA, WB, IP
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:Lot Dependent
推荐稀释比（WB）:1:1000
推荐稀释比（WB Brain）:1:1000
推荐稀释比（IP）:40ul of antibody per 1mg lysate
- 说明书：
Our Anti-Potassium Chloride Cotransporter (KCC2) (Ser940) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat Potassium Chloride Cotransporter (KCC2) (Ser940) and is antigen affinity purified from pooled serum. It is great for use in WB, IP.
