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Anti-Synaptojanin 1 Antibody
Anti-Synaptojanin 1 Antibody
- 中文名称：
- Anti-Synaptojanin 1 Antibody
- 英文名称：
- Anti-Synaptojanin 1 Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- 1936-SYNJt
- 规格：
- 25 µL
- 保存建议：
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- 背景资料：
- Synaptojanin is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms; one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues (Ramjaun AR & McPherson PS, 1996). The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down’s syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidylinositol-4,5- bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice (Voronov SV et al., 2008).
- 货期：
- 3-4周
- 来源宿主：
- Mouse
- 反应种属：
- Rat
- 应用：
- ELISA, WB, IHC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:1 mg/ml
推荐稀释比（WB）:1:1000
推荐稀释比（WB Brain）:1:1000
推荐稀释比（IHC）:1:100
- 说明书：
Our Anti-Synaptojanin 1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects rat Synaptojanin 1 and is Protein G purified. It is great for use in WB, IHC.
