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Anti-URP1 (Kindlin1) Antibody
Anti-URP1 (Kindlin1) Antibody
- 中文名称：
- Anti-URP1 (Kindlin1) Antibody
- 英文名称：
- Anti-URP1 (Kindlin1) Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- 24360
- 规格：
- 100 µL
- 保存建议：
- Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
- 背景资料：
- Due to a concerted effort to identify biomarkers for lung and colon carcinomas by genome-wide transcriptional profiling, the identification and cloning of one such gene as well as two additional closely related genes was achieved. Due to the strong sequence homology to the C. elegans UNC-112 a novel gene gene was named URP1, for UNC-112 related protein. Another novel related gene, URP2 and the previously discovered MIG-2 gene was also identified. Transcriptional analysis shows that only URP1 is significantly differentially regulated, being over-expressed in 70% of the colon carcinomas and 60% of the lung carcinomas tested. Quantification of URP1 expression by qRT-PCR showed up-regulation of the gene by 60-fold in lung tumors and up to nearly 6-fold in colon tumors. Northern blot analysis of URP1 indicates that normal expression is restricted to neuromuscular tissues. In contrast, the expression of URP2 appears to be confined primarily to tissues of the immune system. URP1 has the potential to be one of the most important prognostic and diagnostic markers of colon or lung cancer.
- 货期：
- 3-4周
- 来源宿主：
- Rabbit
- 反应种属：
- Bovine, Canine, Human, Mouse, Non-Human Primate, Rat, Xenopus
- 应用：
- WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
推荐稀释比（WB）:1:500-1:1000
Our URP1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects bovine, canine, human, mouse, non-human primate, rat, Xenopus URP1 and is antigen affinity purified. It is great for use in WB.
