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Anti-ZNRF2 Antibody
Anti-ZNRF2 Antibody
- 中文名称：
- Anti-ZNRF2 Antibody
- 英文名称：
- Anti-ZNRF2 Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- 24390
- 规格：
- 100 µL
- 保存建议：
- Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
- 背景资料：
- Protein ubiquitination has been implicated recently in neural development, plasticity, and degeneration. ZNRF1/nin283, is a protein with a unique, evolutionarily conserved C-terminal domain containing a juxtaposed zinc finger/RING finger combination. ZNRF2, is another novel member of the family of ZNRF E3 ubiquitin ligases. Both ZNRF1 and ZNRF2 have E3 ubiquitin ligase activity and are highly expressed in the nervous system, particularly during development. In neurons, ZNRF proteins are located in different compartments within the presynaptic terminal: ZNRF1 is associated with synaptic vesicle membranes, whereas ZNRF2 is present in presynaptic plasma membranes. Data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity.
- 货期：
- 3-4周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
推荐稀释比（WB）:1:500-1:1000
Our ZNRF2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human ZNRF2 and is antigen affinity purified. It is great for use in WB.
