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Lamin A/C
Lamin A/C
- 中文名称：
- Lamin A/C
- 英文名称：
- Lamin A/C
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA76712
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- The antibody can be stored at 2 degree - 8 degree C for 12 months without detectable loss of activity. Avoidrepeated freeze-thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Chicken
- 反应种属：
- Human, Mouse, Rat, Primate, Dog, Equine
- 应用：
- IF (Immunofluorescence), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:Chicken IgY
克隆号:N/A
特异性:N/A
纯度:N/A
形式：Liquid. Supplied as an aliquot ofconcentrated IgY preparationplus 5mM NaN3
浓度：N/A
- 说明书：
Lamin A and lamin C are members of the intermediate filament protein family and are located in the nucleus where they function as skeletal components of the inner nuclear membrane. The two proteins are generated by alternate transcription from the single LMNA gene. Lamin A has a molecular weight of about 74kDa while lamin C is 65kDa. The lamin A protein includes a C-terminal segment of 98 amino acids missing from lamin C, while lamin C has a unique C-terminal 6 amino acid peptide not present in lamin A. As a result antibodies raised against lamin A are almost certain bind to lamin C. During cell division the nuclear lamina breaks down and lamin A/C containing filaments depolymerize, this being regulated by phosphorylation by cyclin dependent protein kinase 1. Mutations in the lamin A/C gene are associated with several serious human diseases.
This antibody was raised against full length recombinant human lamin A, binds human lamin C, and works with the rodent protein also.
