Anti-EGFRvIII [806]-Anti-EGFRvIII [806]-一抗检测抗体 - 北京博蕾德生物科技有限公司

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: Anti-EGFRvIII [806]

Anti-EGFRvIII [806]

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中文名称：: Anti-EGFRvIII [806]

英文名称：: Anti-EGFRvIII [806]

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA72335

规格：: 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg

保存建议：: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

货期：: 6-8周

来源宿主：: N/A

反应种属：: Human

应用：: IHC (Immunohistochemistry), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:N/A
同型:Rabbit IgG kappa
克隆号:[806]
特异性:This antibody is specific for the human delta2-7 epidermal growth factor receptor (de2-7 EGFR or EGFRvIII) which is a truncated version of the EGFR commonly expressed in glioma. This antibody does not bind wild type EGF receptor. Studies have shown that it binds a cryptic epitope on the EGFR in the region between amino acids 287-302, and it is suggested that breaking the disulfide bond preceding the epitope might allow the CR1 domain to open up sufficiently for antibody binding.
纯度:Purified. Protein A affinity purified
形式：PBS with 0.02% Proclin 300.
浓度：1mg/ml

说明书：

The original antibody was generated by immunization of mice with NR6 mouse fibroblasts expressing the truncated de2-7 EGFR.
Describes the generation of this antibody and examines the antitumor activity of this antibody against human tumor xenografts grown in nude mice.
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

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