Anti-EGFRvIII [806]-Anti-EGFRvIII [806]-一抗检测抗体 - 北京博蕾德生物科技有限公司

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: Anti-EGFRvIII [806]

Anti-EGFRvIII [806]

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中文名称：: Anti-EGFRvIII [806]

英文名称：: Anti-EGFRvIII [806]

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA72336

规格：: 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg

保存建议：: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

货期：: 6-8周

来源宿主：: N/A

反应种属：: Human

应用：: IHC (Immunohistochemistry), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry)

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:N/A
同型:Mouse IgG2b kappa
克隆号:[806]
特异性:This antibody is specific for the human delta2-7 epidermal growth factor receptor (de2-7 EGFR or EGFRvIII) which is a truncated version of the EGFR commonly expressed in glioma. This antibody does not bind wild type EGF receptor. Studies have shown that it binds a cryptic epitope on the EGFR in the region between amino acids 287-302, and it is suggested that breaking the disulfide bond preceding the epitope might allow the CR1 domain to open up sufficiently for antibody binding.
纯度:Purified. Protein A affinity purified
形式：PBS with 0.02% Proclin 300.
浓度：1mg/ml

说明书：

The original antibody was generated by immunization of mice with NR6 mouse fibroblasts expressing the truncated de2-7 EGFR.
Describes the generation of this antibody and examines the antitumor activity of this antibody against human tumor xenografts grown in nude mice.

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