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Syncytin 2 Blocking Peptide
Syncytin 2 Blocking Peptide
- 中文名称：
- Syncytin 2 Blocking Peptide
- 英文名称：
- Syncytin 2 Blocking Peptide
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA226378
- 规格：
- 0.25 mg|2x0.25 mg|3x0.25 mg|4x0.25 mg|5x0.25 mg
- 保存建议：
- Store at -20 degree C for long term storage.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Antigenic Blocking Peptide
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Overview: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732).1 Publication Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).
Peptide Description: Synthetic peptide taken within amino acid region 80-130 on human Syncytin-2 protein.
Structure: Contains the CKS-17 immunosuppressive domain present in many retroviral envelope proteins. As a synthetic peptide, it inhibits immune function in vitro and in vivo.
Expression: Expressed at higher level in placenta. Expressed at lower level in adrenal, bone marrow, brain, breast, colon, kidney, lung, ovary, peripheral blood lymphocytes, prostate, skin, spleen, testis, thymus, thyroid, trachea.
