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CXCR7 Peptide
CXCR7 Peptide
- 中文名称：
- CXCR7 Peptide
- 英文名称：
- CXCR7 Peptide
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA75993
- 规格：
- 0.25 mg|2x0.25 mg|3x0.25 mg|4x0.25 mg|5x0.25 mg
- 保存建议：
- -20 degree C for long term storage
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Synthetic Peptide
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Antigenic Blocking Peptide Chemokine (C-X-C motif) receptor 7 Antibody
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival.
