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Anti-PAK-1,2,3 (Thr402) Antibody
Anti-PAK-1,2,3 (Thr402) Antibody
- 中文名称：
- Anti-PAK-1,2,3 (Thr402) Antibody
- 英文名称：
- Anti-PAK-1,2,3 (Thr402) Antibody
- 品牌：
- phosphosolutions
- 品牌介绍：
- PhosphoSolutions公司成立于2001年。Michael D. Browning, John W. Haycock和Andrew J. Czernik，他们都在Paul Greengard博士的实验室工作过，Paul Greengard博士是2000年诺贝尔医学奖的共同获得者因为他在神经系统信号转导中蛋白质磷酸化的作用。这一专业知识使我们主要关注神经科学领域感兴趣的蛋白质。
- 货号：
- p187-402t
- 规格：
- 25 µL
- 保存建议：
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- 背景资料：
- In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: α-PAK (also known as PAK-1) and β-PAK (also known as PAK-3) are mostly brain-specific, while γ-PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003). Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004). PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003; Walter et al., 1998). Autophosphorylation of Thr-402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).
- 货期：
- 3-4周
- 来源宿主：
- Rabbit
- 反应种属：
- Mouse and Rat
- 应用：
- ELISA, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:Lot Dependent
推荐稀释比（WB）:1:1000
推荐稀释比（WB Brain）:1:1000
- 说明书：
Our Anti-PAK-1,2,3 (Thr402) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat PAK-1,2,3 (Thr402) and is antigen affinity purified from pooled serum. It is great for use in WB.
